Skip to content

Diabetes T2 – Improves blood cholesterol

Improves blood cholesterol

Evidence summary

Blood cholesterol responses to exercise are mixed but may result in a small reduction in LDL cholesterol. Combined weight loss through dietary modification combined with exercise may be more effective than aerobic exercise training alone (Bruno et al., 2012; Pi-Sunyer et al., 2007; Wing, 2010).

Quality of evidence

Low quality

Strength of recommendation



Existing evidence suggests that some patients benefit from being more active, particularly in combination with dietary modification.


Bruno RM, Penno G, Daniele G, Pucci L, Lucchesi D, Stea F, Landini L, Cartoni G, Taddei S, Ghiadoni L, Del Prato S. Type 2 diabetes mellitus worsens arterial stiffness in hypertensive patients through endothelial dysfunction.  Diabetologia. 2012 Jun;55(6):1847-55.

Pi-Sunyer X, Blackburn G, Brancati FL, Bray GA, Bright R, Clark JM, Curtis JM, Espeland MA, Foreyt JP, Graves K, Haffner SM, Harrison B, Hill JO, Horton ES, Jakicic J, Jeffery RW, Johnson KC, Kahn S, Kelley DE, Kitabchi AE, Knowler WC, Lewis CE, Maschak-Carey BJ, Montgomery B, Nathan DM, Patricio J, Peters A, Redmon JB, Reeves RS, Ryan DH, Safford M, Van Dorsten B, Wadden TA, Wagenknecht L, Wesche-Thobaben J, Wing RR, Yanovski SZ. Reduction in weight and cardiovascular disease risk factors in individuals with type 2 diabetes: one-year results of the look AHEAD trial. Look AHEAD Research Group Diabetes Care. 2007 Jun;30(6):1374-83.

Wing RR. Long-term effects of a lifestyle intervention on weight and cardiovascular risk factors in individuals with type 2 diabetes mellitus: four-year results of the Look AHEAD trial. Arch Intern Med. 2010 Sep 27;170(17):1566-75.