A Cochrane review identified a significant improvement in fatigue in those with fibromyalgia undertaking resistance exercise interventions . Their meta-analysis of two RCTs demonstrated a large improvement in the intervention group, with the Mean Difference -14.66 on a 0-100 scale (-20.55 to -8.77).
Quality of evidence
Strength of recommendation
Regular physical activity that includes a degree of resistance exercise is likely to improve fatigue in those with chronic musculoskeletal pain. There is no evidence to suggest that regular physical activity has a negative impact on fatigue in this population.
1 Busch AJ, Barber KAR, Overend TJ, et al.Exercise for treating fibromyalgia syndrome (Review). Cochrane Database Syst RevPublished Online First: 2007. doi:10.1002/14651858.CD003786.pub2.Copyright