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COPD – Improved Quality of Life

Evidence Summary

A large body of good quality interventional data shows an improvement in quality of life as measured by outcome scores.

Quality of Evidence

Grade B – moderate quality. Evidence comes from randomised controlled trials

Strength of recommendation

Grade 1 – strong recommendation. Clinical and patient consensus is that physical activity can improve quality of life scores. On the basis of the existing evidence, clinical opinion is that all or most patients will be best served by following this piece of evidence. The vast majority of patients would choose to follow this evidence when given the choice

Conclusion

Strong recommendations can be applied to most patients in most circumstances and should be followed unless there are compelling reasons to do otherwise

1) Kotianou (ERS Congress Abstract, 2010)36

Continuous vs Interval Training (40 mins 3x weekly, 30 sessions)- 46 participants

QOL: change in SGRQ13.9/6.9

2) Mador (J Cardiopulm Rehabil Prev, 2009)37

HIT vs LIT (3x weekly 8 weeks), 252 participants

Functional Capacity: 6MWD 158/106m,

QoL domains: change in fatigue: 3.1/2.8, change in dyspnoea: 4.4/5.4

3) Puhan (Annals of Internal Medicine, 2006)39

Continuous vs Interval Training (12-15 sessions over 3 weeks)

QOL: CRQ improved 1/1.02,

4) Santos (Respiratory Care, 2015)40

HIT vs LIT (3x weekly 8 weeks), 34 participants

QOL: change in SGRQ: 14.7/10.6

5) Vogliatzis (ERJ, 2002)44

Continuous vs Interval Training (40 mins 3x weekly 12 weeks) 36 participants

QOL: change in SGRQ: 5

6) Amin (BMC Pulm Med, 2014)45