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IRD CTD – Enhance mood

Enhance mood by Moving more:

Low mood and depression can be common in people with connective tissue disease.  Exercise interventions have been shown to  improve depression scores in SLE[1].  Furthermore from the compelling body of evidence for the general population, being physical active has been shown to improved self-esteem and quality of life [2]. Another reason to motivate patients to become more physical active.

Quality of evidence:

Moderate Quality

Strength of recommendation

Strong Recommendation


Low mood and depression are common in connective tissues and there is evidence to suggest physical activity can help improve mood and depression scores.


  1. Dwyer T, Durcan L, Wilson F. Exercise and physical activity in systemic lupus erythematosus: A systematic review with meta-analyses. Semin Arthritis Rheum. 2017;47(2):204-215.
  2. Department of Health. Start Active, Stay Active. In: Strategy; 201